Introduction
STISPAS is a trusted formulation combining Mefenamic Acid and Dicyclomine Hydrochloride, designed for effective management of abdominal pain and spasms. This dual-action tablet works by relieving pain, reducing inflammation, and relaxing smooth muscles of the gastrointestinal and uterine tract. Manufactured under WHO-GMP certified standards, STISPAS ensures high safety, quality, and efficacy. It is especially beneficial in conditions such as menstrual cramps, irritable bowel syndrome, and other spasm-related abdominal discomforts.
Composition & Mechanism of Action
- Mefenamic Acid: A non-steroidal anti-inflammatory drug (NSAID) that helps relieve pain and reduces inflammation by inhibiting prostaglandin synthesis.
- Dicyclomine Hydrochloride: An antispasmodic agent that works by relaxing smooth muscles of the gut and uterus, controlling cramps and spasms.
This combination provides both symptomatic pain relief and spasm control, offering faster recovery and better patient comfort compared to single-ingredient therapies.
Therapeutic Indications
STISPAS is prescribed for a wide range of pain and spasm-related conditions, such as:
- Menstrual Cramps (Primary Dysmenorrhea): Relieves uterine contractions and pelvic pain.
- Abdominal Pain & Spasms: Effective in gastrointestinal and uterine spasmodic conditions.
- Irritable Bowel Syndrome (IBS): Provides relief from cramping and bloating.
- Gastrointestinal Colic: Reduces pain associated with intestinal spasms.
- Biliary & Ureteric Spasms: Helps in managing pain caused by gallbladder or urinary tract spasms.
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Functional Abdominal Pain: Useful in managing recurrent abdominal discomfort.

Dosage & Administration
- Recommended Dose: As prescribed by a physician, depending on the patient’s condition.
- Administration: Best taken after meals to minimize gastric irritation.
- Treatment Duration: Typically short-term, during episodes of pain and cramps.
- Special Considerations: Elderly patients and those with kidney or liver impairment require medical supervision.
- Missed Dose: If missed, take as soon as remembered, but avoid doubling the dose.
Benefits of STISPAS
- Dual Action Formula: Combines pain relief with spasm control for complete comfort.
- Fast Symptom Relief: Works quickly against abdominal pain and menstrual cramps.
- Broad Applications: Effective for both gynecological and gastrointestinal conditions.
- Improves Quality of Life: Reduces discomfort, allowing patients to return to normal activities.
- Convenient Dosage Form: Available in tablet form for easy use.
- Assured Quality: Produced under WHO-GMP standards ensuring safety and reliability.
Safety & Precautions
While STISPAS is generally well tolerated, some patients may experience mild side effects such as nausea, dizziness, dry mouth, or gastrointestinal upset.
- Contraindications: Avoid use in patients with kidney disease, liver impairment, peptic ulcers, or hypersensitivity to NSAIDs or antispasmodics.
- Drug Interactions: May interact with anticoagulants, antihypertensives, and other NSAIDs.
- Pregnancy & Lactation: Should only be taken if prescribed by a healthcare provider.
- Storage: Keep in a cool, dry place away from direct sunlight and moisture.
Conclusion
STISPAS (Mefenamic Acid + Dicyclomine HCl Tablets) is a clinically effective and safe solution for managing abdominal pain, cramps, and spasmodic conditions. With its dual mechanism of action, it ensures rapid relief and long-lasting comfort for patients. Whether for menstrual pain or gastrointestinal spasms, STISPAS provides a dependable treatment option backed by WHO-GMP quality assurance.